Compile Data Set for Download or QSAR
Found 19 of ic50 data for polymerid = 50004089
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50536679(CHEMBL4568087)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of full-length recombinant human GST-tagged NEK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27X5PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50265242(3-(4-(4-iodophenoxy)thieno[2,3-c]pyridin-2-yl)-1,2...)copy SMILEScopy InChI
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 74.2nMAssay Description:Inhibition of human NEK4 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KB8PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50613381(CHEMBL5278787)copy SMILES
Affinity DataIC50: 80nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of human NEK4 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50536675(CHEMBL4569508)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of full-length recombinant human GST-tagged NEK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27X5PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50381716(ABT-348 | ILORASERTIB | US8722890, 1 | US8722890, ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50536678(CHEMBL4550702)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of full-length recombinant human GST-tagged NEK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27X5PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50613379(CHEMBL1994830)copy SMILES
Affinity DataIC50: 316nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50536681(CHEMBL4552628)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of full-length recombinant human GST-tagged NEK4 expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27X5PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50613380(CHEMBL1988153)copy SMILES
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50613378(CHEMBL1997822)copy SMILES
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50396534(CHEMBL2171124)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of NEK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222VWPPubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM121388(US8722890, 3)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full-length human NEK4 P225A mutant using myelin basic protein as substrate measured after 40 mins in presence of [gamma33P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93FGPubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50499634(CHEMBL3741589)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NEK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5CV4PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged NEK4 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N018JCPubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NEK4 using MBP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WT8PubMed
TargetSerine/threonine-protein kinase Nek4(Homo sapiens (Human))
Merck and Co.

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged NEK4 expressed in baculovirus expression system using serine/threonine-7 peptide as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed